Dr. Zobaer Al Mahmud
(Associate Professor)Department of Clinical Pharmacy and Pharmacology
| Degree Name | Group/Major Subject | Board/Institute | Country | Passing Year |
|---|---|---|---|---|
| Ph.D. | Molecular Pharmacology | University of Glasgow | United Kingdom | 2019 |
| Masters | Clinical Pharmacy and Pharmacology | University of Dhaka | Bangladesh | 2008 |
| Bachelor | Pharmacy | University of Dhaka | Bangladesh | 2007 |
| Title | Organization | Location | From Date | To Date | |
|---|---|---|---|---|---|
| No experience is found | |||||
Research Interest
| Subject | Description | Research Interest (Goal, Target Indicator) |
|---|---|---|
| GPCR Pharmacology | My research on GPCR pharmacology includes defining the role of G protein-coupled receptor 84 (GPR84) signalling in pathophysiology of several metablic/inflammatory disorders including osteoarthritis, diabetes mellitus, NAFLD and hepatic fibrosis using a range of animal disease models. We are also investigating the in-vivo characterization of novel small molecule drug candidates targeting this receptor. |
|
| Pharmacogenomics | Currently I am evaluating the effect of genetic variations in genes encoding GPCRs, VEGF, VEGFRs, cytokines and chemokines on disease risk/susceptibility in Bangladeshi demographics. Major objectives of these genetic studies is to find out novel and effective genetic/vascular/immunological blood-based biomarker(s) for the hard to diagnose diseases. |
Project/Research Supervision
| Level of Study | Title | Supervisor | Co-Supervisor(s) | Name of Student(s) | Area of Research | Current Completion |
|---|---|---|---|---|---|---|
| No project/research supervision is found | ||||||
Project/Research Work
| Subject | Project Name | Source of Fund | From Date | To Date | Collaboration |
|---|---|---|---|---|---|
| GPCR pharmacology ( In vivo) | In-vivo animal model studies characterizing the role of GPR84 in pathogenesis of Type II diabetes mellitus, hepatic fibrosis and osteoarthritis: | 01-02-2024 |
Invited Talk
| SL | Invited Talk |
|---|---|
| No invited talk is found | |
| SL | Collaboration & Membership Name | Type | Membership Year | Expire Year |
|---|---|---|---|---|
| No Collaboration & Membership is found | ||||
| Journal Article | |
|---|---|
| 1 |
Nisat Sarmin, A. S. M. Roknuzzaman, Tashfiya Zaman Mouree, Md. Rabiul Islam and Zobaer Al Mahmud : Evaluation of serum interleukin-12 and interleukin-4 as potential biomarkers for the diagnosis of major depressive disorder,
Scientific Reports (impact factor:4.6 (2022)) , vol.14 , no.Article number 1652, (2024) Nature Portfolio , pp.11 , 2024
.
|
| 2 |
Jannatul Nayem, Rapty Sarker, A S M Roknuzzaman, M M A Shalahuddin Qusar, Sheikh Zahir Raihan, Md Rabiul Islam and Zobaer Al Mahmud : Altered serum TNF-α and MCP-4 levels are associated with the pathophysiology of major depressive disorder: A case-control study results,
PLoS One (impact factor:3.72 (2022)) , vol.18 , no.(11):e0294288 PLOS , pp.17 , 2023
.
|
| 3 |
Sara Marsango, Richard J. Ward, Laura Jenkins, Adrian J. Butcher, Zobaer Al Mahmud, Louis Dwomoh, Falko Nagel, Stefan Schulz, Irina G. Tikhonova, Andrew B. Tobin and Graeme Milligan : Selective phosphorylation of threonine residues defines GPR84-arrestin interactions of biased ligands,
Journal of Biological Chemistry (impact factor:5.485) , vol.298 , no.5:101932 American Society for Biochemistry and Molecular Biology , pp.15 , 2022
.
|
| 4 |
Laura Jenkins, Sara Marsango, Sarah Mancini, Zobaer Al Mahmud, Angus Morrison, Stuart P. McElroy, Kirstie A. Bennett, Matt Barnes, Andrew B. Tobin, Irina G. Tikhonova and Graeme Milligan : Discovery and Characterization of Novel Antagonists of the Proinflammatory Orphan Receptor GPR84,
ACS Pharmacology and Translational Science (impact factor:6 (2022)) , vol.4 , no.5 American Chemical Society , pp.1598–1613 , 2021
.
|
| 5 |
Sarah J. Mancini, Zobaer Al Mahmud, Laura Jenkins, Daniele Bolognini, Robert Newman, Matt Barnes, Michelle E. Edye, Stephen B. McMahon, Andrew B. Tobin and Graeme Milligan : On-target and off-target effects of novel orthosteric and allosteric activators of GPR84,
Scientific Reports (impact factor:4.6 (2022)) , vol.9 , no.Article number 1861 (2019) Nature Portfolio , pp.15 , 2019
.
|
| 6 |
Zobaer Al Mahmud, Laura Jenkins, Trond Ulven, Frédéric Labéguère, Romain Gosmini, Steve De Vos, Brian D. Hudson, Irina G. Tikhonova and Graeme Milligan : Three classes of ligands each bind to distinct sites on the orphan G protein-coupled receptor GPR84,
Scientific Reports (impact factor:4.6 (2022)) , vol.7 , no.Article number: 17953 (2017) Nature Portfolio , pp.15 , 2017
.
|
| 7 |
Amlan Ganguly, Zobaer Al Mahmud, Sajal Kumar Saha and S M Abdur Rahman : Evaluation of antinociceptive and antidiarrhoeal properties of Manilkara zapota leaves in Swiss albino mice,
Pharmaceutical Biology (impact factor:3.8 (2022)) , vol.54 , no.8 Taylor & Francis , pp.1413-9 , 2016
.
|
| Award Type | Title | Year | Country | Description |
|---|---|---|---|---|
| Local | Writer Sarder Joyen-Uddin Gold Medal | 2009 | Bangladesh | |
| Local | ACI Abdul Mukit Gold Medal | 2008 | Bangladesh | |
| Local | Deans Award | 2008 | Bangladesh |
Dr. Zobaer Al Mahmud
Associate Professor
Department of Clinical Pharmacy and Pharmacology
Faculty of Pharmacy
Email: zalmahmud@du.ac.bd
Mobile (Dept): +88-01301596950
Mobile (Personal): 01301596950